Principle and applications of gas chromatography

What factors influence the separation of components in gas chromatography?

Separation of components in GC is affected by vapor pressure, column length, analyte polarity relative to stationary phase polarity on the column, column and oven temperature, carrier gas flow rate and sample amount. injected.

What is the most used detector in gas chromatography?

There are many types of detectors used in gas chromatography, such as flame ionization detector (FID), thermal conductivity detector (TCD), mass spectrometer (GC/MS), thermal conductivity detector (TCD) and the gas detector. ECD), but among these, the flame ionization detector is the most widely used detector in gas chromatography.

What is the main difference between GC-MS and LC-MS?

GC-MS and LC-MS are separation techniques used to separate compounds. The main difference between GC-MS and LC-MS is that the mobile phase of GC-MS uses inert gases such as nitrogen or helium while LC-MS uses a solvent or a mixture of solvents as mobile phase. .

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