Which equation describes the rate of dissolution of the drug from the pills?

According to the USP, a drug is believed to dissolve rapidly when at least 85% of the claimed amount of the molecule dissolves within 30 minutes, using the USP-I apparatus at 100 rpm or 50 rpm min for USP-II device. , in a volume of 900 ml or less in any media, such as 0.1 n HCl, pH 4.5 buffer, pH 6.8 buffer.


Dissolution Rate Equation

dw/dt= ks (Csat-Csol)

Where

dw/ dt = are the rate of dissolution

k = a dissolution constant

S = area of ​​the solid

C sat = concentration of a saturated solution

C sol = the concentration at a given time

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Jose Hullgren (Laboratory Analist)

Hello to all readers, my name is Jose Hullgren, it is a pleasure to present you this website of my authorship, I am currently working as a laboratory analyst and for the last 10 years I have been working in the pharmaceutical industry. The main idea of this page is to provide relevant information in the field of the pharmaceutical industry above all. We also cover different areas of chemistry and sciences in general that we find interesting. Perfil Linkedin

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