However, due to the high quality of the granules formed in the case of material uniformity and physico-chemical properties, such as bulk density, granulation size, humidity, hardness, compressibility, etc. , granulation faces many challenges, through the chemical and physical stability of the drug.
Granulation processes are divided into two types: wet granulation and dry granulation; in wet granulation, the process which uses liquid granulation and dry granulation which uses solids.